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BIOINFORMATICS

Wahlmodul 2: Bioinformatik (7,5 ECTS-AP, 5 SSt) [VO 2 104540] [UE 3 104541]

LECTURER

Hubert Hackl, Dietmar Rieder

LOCATION

Rechnerraum 19

UNITS

Tu 4 June	[09:00-12:00] [13:00-16:00]	Lecture	rr19	Hubert Hackl
We 5 June	[09:00-12:00] [13:00-16:00]	Lecture	rr19	Hubert Hackl
Th 6 June	[09:00-12:00] [13:00-16:00]	Lecture	rr19	Hubert Hackl
Fr 7 June	[09:00-17:00]	Computer Lab	rr19	Dietmar Rieder
Mo 10 June	[09:00-12:00] [13:00-15:00]	Lecture/Seminarpreparation Seminar/Presentations	rr19 rr19	Hubert Hackl DR, HH
Tu 11 June	[09:00-17:00]	Computer Lab	rr19	Dietmar Rieder
We 12 June	[09:00-12:00]	Computer Lab	rr19	Dietmar Rieder
Th 13 June	[09:00-12:00] [14:00-17:00]	Exampreparation Computer Lab	rr19 rr19	Dietmar Rieder
Fr 14 June	[09:00-12:00] [13:00-15:00]	Computer Lab Written Exam	rr19 rr19	Dietmar Rieder Hubert Hackl

NOTES

I Transcriptional regulation, II Sequence analyses, III Gene expression analyses	[pdf]
IV Functional analyses (pathways, enrichment, networks), V Single cell analyses (scRNAseq)	[pdf]
Exercises - Computer Lab	Link

SEMINAR TOPICS

Evolution of antibodies using protein language models

Phenotype of single cell RNAseq subpopultaions (Scissor)

Neoantigen prediction

Transcriptional brain atlas

Pathway responsive genes for activity inference (PROGENy)

Deep learning for TCR prediction

Immunogenicity testing with multimers

Single-cell RNA-seq using microfluidics

Transcriptomics based signaling pathway analysis

Genome architecture mapping

Modulator inference by network dynamics (MINDy)

Phylogenetic trees (REALPHY)

Single cell RNAseq in Pancreas

Sequenza: allele specific copy number from tumor sequencing

Network motifs

ChIP-seq in myogenesis

Time series network interference (TSNI)

Tumor immune microenvironment in ccRCC