BiocenterMedical University of Innsbruck
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Theses

PhD theses

Raphael Gronauer. Integrative multi-omics analyses to delineate the cancer immunome and therapeutic vulnerability affected by deficient DNA repair mechanisms. 2024
Alexander Kirchmair. Metabolic reprogramming during CD8+ T cell differentiation. 2024
Georgios Fotakis. The impact of conventional therapy on immunoediting and tumor evolution in microsatellite stable (MSS) colorectal cancer (CRC). 2023
Gregor Sturm. Dissecting immune-epithelial crosstalk using data integration. 2023
Christina Plattner. Functional precision profiling for colorectal cancer. 2023
Michaela Willi. Super-enhancers and genetic boundaries in the mammary gland. 2017
Mirjana Efremova. Investigating immunoediting of the cancer genome. 2017
Mihaela Angelova. Immunogenicity of human colorectal carcinoma. 2015
Andreas Dander. Integration of next-generation sequencing data and whole-slide bioimages for personalized oncology. 2014

Master theses

Lukas Küng. Immunomodulation by epigenetically activated endogenous retroelements in ovarian cancer. 2025
Katja Rungger. Intratumoral microorganisms and their effects on antitumor immunity. 2024
Elena Frisch. Analysis of signaling responses to kinase inhibitors using mouse organoids. 2023
Matthias Winkler. Immunogenic cell death by kinase inhibitor treatment of tumor organoids. 2023
Marie Theres Elling. Molecular and metabolic characterization of cancer associated fibroblasts. 2022
Leonie Madersbacher. Effects of PARP inhibition on the transcriptome in BRCA1 wild-type and BRCA1 deficient ovarian cancer cell lines. 2022
Gabriel Floriani. Viral and tumour associated antigen prediction for a variety of class I HLA alleles. 2022
Stefanie Estermann. Histological and metabolic characterization of murine CRC organoids. 2022
Leonie Madersbacher. Synthetic lethal interactions determine the therapeutic vulnerability of cancer. 2021
Valentin Marteau. Combining a systems biology approach with a model of in vitro human cortical brain development to study schizophrenia. 2020
Hendrik Gottschling. Immune independent analysis of tumour sample transcriptomes. 2020
Markus Ausserhofer. Development and validation of a pipeline for tumor epitope prediction. 2020
Matthias Leitner. Neoepitope prediction for personalized cancer immunotherapy. 2020
Verena Vogi. Influence of metabolic processes, individual metabolites and nutrients on T-Cell responses. 2019
Nina Huber. Investigating the role of the nuclear receptor NR4A1 in T cell activation and T cell glucose metabolism. 2019
Niloofar Nemati. Investigation of the role of nuclear receptor activity in the cytotoxic T cell activation - exhaustion axis. 2019
Sophia Daum. Development of an in vitro system for testing drug combinations. 2019
Yeliz Cengiz. Establishment of a drug treatment protocol fro organoid derived from colorectal cancer of human patients. 2019
Christoph Schatz. Development of an analysis tool to identify cancer type specific microRNA targets. 2019
Johannes Ruepp. Analysis of histone and protein acetylation in human adipocytes. 2016
Christina Plattner. Gene and microRNA expression based molecular cancer classification. 2015
Benno Weber. Modeling cancer metabolism. 2015
Clemens Mayer. Modelling cancer stem cells. 2014
Dominik Schweiger. SPARQL Graph: Graphical query builder for biological federated SPARQL queries. 2014
Stefan Scondo. Evaluation of next generation sequencing analysis techniques
Alvaro Ospina. Development of a chemotaxis model for tumor-immune cell interaction. 2013
Matthias Baldauf. Development of an application for management of high content images. 2013
Michaela Willi. Mapping expression data onto genome-scale human metabolic models. 2012
Prioritization of disease driving candidate genes based on various public data sources in the context of rare Mendelian diseases
GPU computing and its practical applications in a HPC infrastructure for Clinical Bioinformatics



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