NOTES
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1 NCBI, BLAST |
1.1 Find difference between insulin sequence in pig and human. Document and discuss points 1-9 |
1.2 Show that sequence coding for C-peptide is less conserved than sequences coding for the A-chain and the B-chain. |
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2 ENTREZ, OMIM
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| Find information on SICKLE CELL ANEMIA and KABUKI SYNDROM using ENTREZ and OMIM. |
2.1 Which genes/proteins are involved?
2.2 On which chromosome (arm, cytogenetic band) genes are located?
2.3 What is the position and strand on the human reference genome assembly (GRCh38/hg38)?
2.4 Can these genes also be found in the mouse?
2.5 Are there common mutations i.e. non-synonymous single nucleotide polymorphism (SNPs) known?
[e.g. see global minor allele frequency (MAF) in gene view of dbSNP]
2.6 What is the function of the encoded proteins?
2.7 Find recent publications
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LINKS
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